Clinical Research Directory

Inclusion Criteria: * Chronic coronary syndrome or acute coronary syndrome diagnosis (per ESC guidelines). * De novo obstructive CAD: ≥50% left main stenosis, or any stenosis ≥70%, or FFR \<0.80 in any other major epicardial vessel, or MLA deemed ischemic at intravascular imaging. * OCT assessment of the target segment phenotype prior to lesion preparation and DCB angioplasty. * Successful DCB angioplasty according to DCB ARC criteria. * Patients who underwent DCB-only PCI, or hybrid DCB-DES PCI with at least 20 mm of the target segment treated with DCB. Exclusion Criteria: * Previous revascularization of the target segment with stent. * Hybrid DCB-DES PCI with DCB-treated segment \<20 mm and/or lacking complete OCT assessment of the DCB-treated segment and/or bailout stenting. * Lack of at least 6 months of clinical follow up. * PCI of chronic total occlusion.