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ENROLLING BY INVITATION
NCT07393503
PHASE4

Musculoskeletal Outcomes Using Tylenol/Ibuprofen vs. Oral Steroids in New Injuries

Sponsor: State University of New York at Buffalo

View on ClinicalTrials.gov

Summary

In this pilot study, the investigators aim to compare two short-term pain relief methods administered over the course of 6 days in the setting of acute musculoskeletal (MSK) pain: 1. Methylprednisolone((Medrol)dose pack- standard taper per dose pack instructions 2. Standard of Care (SOC) which includes a combination of Acetaminophen (Tylenol)+Ibuprofen (Motrin) The investigators are interested in studying pain relief regimens for acute injury of any body part among an adult orthopaedic urgent care population.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2025-09-17

Completion Date

2027-01

Last Updated

2026-02-18

Healthy Volunteers

No

Interventions

DRUG

Methylprednisolone 4Mg Tab

Participants follow standard 6- day taper dosing schedule.

DRUG

Acetaminophen 500Mg Tab

Participants follow a 6- day taper dosing schedule.

DRUG

Ibuprofen 200Mg Oral Tablet

Participants follow a 6- day taper dosing schedule.

Locations (1)

UBMD Orthopaedics and Sports Medicine (716 Health)

Buffalo, New York, United States