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Metaphylaxis of Infected Kidney Stones After Percutaneous Nephrolithotripsy
Sponsor: West Kazakhstan Marat Ospanov Medical University
Summary
Kidney stone recurrence, particularly infection-related stones, remains a significant clinical problem after percutaneous nephrolithotripsy (PCNL). Bacterial colonization and persistent infection are recognized contributors to stone recurrence. This study evaluates the effectiveness of intrarenal dioxidine instillation as a metaphylactic measure to reduce recurrence of infection-related kidney stones following PCNL. Patients undergoing PCNL will receive standard treatment, with or without adjunctive intrarenal dioxidine administration. The study aims to assess whether this approach reduces stone recurrence and infection-related complications.
Official title: Evaluation of the Effectiveness of Intrarenal Dioxidine Metaphylaxis for Preventing Recurrence of Infection Stones After Percutaneous Nephrolithotripsy
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
95
Start Date
2026-03-01
Completion Date
2026-12-30
Last Updated
2026-02-11
Healthy Volunteers
No
Interventions
Dioxidine
Intrarenal instillation of dioxidine solution after PCNL to reduce bacterial colonization and prevent recurrence of infection-related stones.
Percutaneous Nephrolithotripsy (PCNL)
Standard percutaneous nephrolithotripsy procedure for removal of kidney stones.
Locations (1)
West Kazakhstan Marat Ospanov Medical University
Aqtöbe, Kazakhstan