Clinical Research Directory

Inclusion Criteria: 1. Patients with ICA occlusion confirmed by CTA, MRA, and cerebral DSA. 2. MRI ASL-confirmed hypoperfusion in the territory of the occluded ICA (decrease of ≥30% compared with the contralateral side) 3. Language comprehension is preserved, with mild or no motor aphasia and no significant cognitive impairment. 4. Patients aged from 18 to 80 years. 5. Modified Rankin Scale (mRS) score 0-2. 6. Informed consent is available from the patient or legal guardian. 7. Accessible and reliable patients for follow-up Exclusion Criteria: 1. Patients with large territorial infarction or marked cerebral atrophy on MRI. 2. No evidence of regional hypoperfusion on ASL MRI relative to the contralateral hemisphere. 3. Patients with a non-functioning STA-MCA bypass 4. Patients aged under 18 5. Patients with severe somatic conditions or mRS score \> 3 6. Patients with bilateral ICA occlusion, neurovascular disease (cerebral aneurysm or arteriovenous malformation) 7. Patients with Contraindications to MRI, CTA, or DSA 8. Cardiac conditions associated with a high risk of cerebral embolism, including prosthetic heart valves, infective endocarditis, intracardiac thrombus, sick sinus syndrome, cardiac myxoma, or cardiomyopathy with left ventricular ejection fraction \<25% (atrial fibrillation, patent foramen ovale, and atrial septal aneurysm are not exclusion criteria). 9. Severe systemic comorbidities, life expectancy \<2 years, or a modified Rankin Scale (mRS) score \>3. 10. Pregnancy. 11. Contraindications to MRI, CTA, DSA, iodinated contrast agents, or antiplatelet therapy required in the perioperative period. 12. Participation in another interventional or experimental trial within the previous 12 months, including studies involving ionizing radiation \-