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UCSF Center for Genome Surgery Biobank and Registry
Sponsor: University of California, San Francisco
Summary
Gene editing approaches (including but not limited to: CRISPR, LNP, AAV, RNAi etc.) for the medical specialty of interventional genomics require (1) determination of the clinical relevance of genomic variants and (2) systematic evaluation of the 'editability' of those variants. Here, we seek to use in silico and in vitro analyses of genomic, cellular, and clinical data/specimens to (1) identify novel pathogenic variants underlying diseases and (2) examine the specificity and efficacy of various gene editing components across the entire human genomic landscape.
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
10000
Start Date
2026-05-01
Completion Date
2050-12
Last Updated
2026-02-09
Healthy Volunteers
Yes
Locations (1)
University of California, San Francisco
San Francisco, California, United States