Clinical Research Directory

Inclusion Criteria: * Obstructive sleep apnoea diagnosis with an AHI of 15-50 events/hour recorded in the baseline polysomnography (PSG) * BMI \< 32 kg/m² * Age \> 18 years old * Able to read, write, and speak Dutch with acceptable visual and auditory acuity * Able and willing to provide informed consent Exclusion Criteria: * Presence of a cardiac pacemaker or implantable cardiac defibrillator or ventriculoperitoneal shunt * Central (non-obstructive) AHI episodes \>5 events/hour recorded in the baseline PSG * Inability to sleep supine * Pregnancy * Inability to undergo DISE * Inability or unwillingness to shave under and around their chin and neck if appropriate * Known inability to complete PSG with a total sleep time of \> 4 hours * The use of other neurostimulatory devices * A diagnosis of periodic leg movement disorder * Awake resting arterial oxygen saturation \<93% (suggesting possible hypoventilation) * Unstable, untreated coronary or peripheral artery disease * Severe arterial hypertension defined as a resting blood pressure (BP) of \>180/110mmHg * Currently employed as a professional driver * Any previous sleep-related driving accident * A past or current condition that in the opinion of the investigator contraindicates enrolment (e.g. chronic substance abuse, severe psychiatric disorders)