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NOT YET RECRUITING
NCT07396714
EARLY_PHASE1

the Efficacy of Ivermectin Alone or With Microneedling in Treatment of Cutaneous Warts.

Sponsor: Assiut University

View on ClinicalTrials.gov

Summary

To compare between the efficacy and safety of topical ivermectin alone, microneedling with topical ivermectin and topical salicylic acid in treatment of cutaneous warts. topical ivermectin 1% will be applied on warts whole night clinical assessment will be done every 2 weeks Microneedling will be performed on the lesion using a microneedling pen type device with a 1-cm tip diameter at a 2-mm depth setting for 2-3 minutes until pinpoint bleebing occurs 1 mL of topical ivermectin 1% will be applied on to the wart tissue. Sessions: Sessions will be performed every 2 weeks until complete cure or for maximum 6 sessions (total 3 month)

Official title: Evaluation of the Efficacy & Safety of Topical Ivermectin Alone or in Combination With Microneedling as Novel Therapeutic Options for Cutaneous Non-genital Warts Versus Topical Salicylic Acid ؛ Randomized Controlled Clinical Trial.

Key Details

Gender

All

Age Range

11 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

88

Start Date

2026-02-01

Completion Date

2027-06-01

Last Updated

2026-02-09

Healthy Volunteers

No

Conditions

Interventions

DRUG

Ivermectin

patients with non-genital cutaneous warts will be treated by topical application of ivermectin : topical ivermectin 1% will be applied under occlusion overnight daily then revaluated every 2 weeks for maximum 12 weeks

DEVICE

microneedling

patients with non-genital cutaneous warts will be treated by microneedling (2mm depth) every 2-weeks until complete clearance or for a maximum of 12weeks

DRUG

Salicylic Acid

patients with non-genital cutaneous warts will be treated by topical application of ivermectin : cotton soaked with topical salicylic acid will be applied under occlusion overnight daily then revaluated every 2 weeks for maximum 12 weeks