Clinical Research Directory
Browse clinical research sites, groups, and studies.
The Application of Intralesional 5-fluorouracil for the Management of Hypertrophic Facial Scars in the Periocular Region Resulting From Trauma and Surgical Procedures in Individuals Aged Over 18 Years
Sponsor: Instituto de Oftalmología Fundación Conde de Valenciana
Summary
To determine the effectiveness of intralesional 5-fluorouracil in objectively reversing hypertrophic scars in the periocular region resulting from trauma or cosmetic surgery.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2025-08-01
Completion Date
2026-08-31
Last Updated
2026-03-04
Healthy Volunteers
No
Conditions
Interventions
Intralesional administration of 5-fluorouracil
For the objective assessment of baseline status and subsequent facial skin changes, the validated Manchester Scar Scale will be used, which is a visual photonumeric scale for evaluating scar quality. This scale assesses six skin parameters, such as color, contour, distortion, texture, and brightness, assigning values from 1 to 4, with 1 indicating the best characteristic and 4 the least desirable
Locations (1)
Instituto de Oftalmologia F.A.P. Conde de Valenciana, I.A.P.
Mexico City, Mexico City, Mexico