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Extended vs. Intermittent Meropenem Infusion in Sepsis Patients in the ICU
Sponsor: Assiut University
Summary
This observational study compares extended versus intermittent beta-lactam infusion in sepsis patients, assessing survival, clinical cure rates, and practical ICU challenges. The findings will guide optimal antibiotic protocols, potentially improving sepsis outcomes through precision dosing strategies.
Official title: "The Impact of Meropenem Strategy on Treatment Efficacy in Sepsis and Septic Shock : Extended vs. Intermittent Dosing in the ICU"
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
OBSERVATIONAL
Enrollment
90
Start Date
2027-10
Completion Date
2028-04
Last Updated
2026-09-01
Healthy Volunteers
No
Conditions
Interventions
Extended beta-lactam antibiotics
Group A will be receiving extended infusion of beta-lactam antibiotic over 4 hours.
Intermittent Beta-lactam antibiotics
Group B will be receiving intermittent infusion of beta-lactam antibiotic over 30 minutes.