Clinical Research Directory

Inclusion Criteria: 1. Patient's aged 18 years more. 2. ASA physical status I-II. 3. Patient with the complain of pain originated from teeth and surrounding structure. 4. Preoperative pain severity is moderate to severe. 5. Patient can be able to make communication about their pain. 6. Patients give consent to attain this research. 7. Patients have others concomitant chronic pain. 8. Patients who will have non-surgical endodontic treatment. 9. Patients who will have non-surgical endodontic retreatment. 10. Patients who will have surgical endodontic treatment. Exclusion Criteria: 1. Patient would not like to attain in research. 2. Patients have any medical condition those are contra indication for study drug. 3. ASA physical status III, IV, V. 4. Patient already under treated any anti convulsent drug. 5. Patient participant in other clinical trials. 6. Lack of motivation or poor adharence to study protocols. 7. Patient with Pregnancy 8. Severe organ dysfunction 9. Patient have Hepatitis B, and other cross infection disease like (HIV) 10. Uncontrolled comorbidities that patient do not fit for endodontic treatment. 11. Severe cognitive impaired patients. 12. History of certain cancers or severe hematological issues.