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Evaluation of the Safety and Efficacy of GLK-321 in Subjects With Demodex Blepharitis
Sponsor: Glaukos Corporation
Summary
This is a randomized, double-masked, placebo-controlled, dose-ranging, parallel-group, multi-center study designed to evaluate the safety and efficacy of GLK-321 in patients with Demodex blepharitis.
Official title: Multicenter, Randomized, Double-Masked, Placebo-Controlled, Parallel Group Phase 2 Trial Evaluating the Safety and Efficacy of GLK-321 in Subjects With Demodex Blepharitis
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
250
Start Date
2025-12-05
Completion Date
2026-11
Last Updated
2026-02-27
Healthy Volunteers
No
Conditions
Interventions
GLK-321 low dose BID
Twice daily administration of low dose GLK-321 to both eyes
GLK-321 mid dose BID
Twice daily administration of mid dose GLK-321 to both eyes
GLK-321 high dose BID
Twice daily administration of high dose GLK-321 to both eyes
GLK-321 high dose QD
Once daily administration of high dose GLK-321 to both eyes
Placebo BID
Twice daily administration of placebo to both eyes
Locations (1)
Glaukos Clinical Study Site
Newport Beach, California, United States