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RECRUITING
NCT07402031

Predicting Weight Loss After Pharmacological or Surgical Treatment in Patients With Obesity

Sponsor: Université Catholique de Louvain

View on ClinicalTrials.gov

Summary

As with other nutritional strategies, the clinical response to bariatric surgery can be highly variable, with weight regain being a frequent occurrence. Recent evidence on anti-obesity medication indicate similar inter-individual variability in clinical response. Among multiples factors, co-occurrence of eating disorders such as binge eating disorder has been implicated in insufficient clinical response. Improving our ability to predict how patients will respond to obesity treatment is necessary in order to tailor the care pathways we offer. The mechanisms involved in disturbances of eating behaviour before and after surgery remain largely unknown. This study aims to identify the predictive factors of weight loss after pharmacological or surgical treatment, as well as the cognitive and biological mechanisms that mediate this effect.

Official title: Research of Predictive Factors of Weight Loss After Pharmacological or Surgical Treatment in Patients Suffering From Obesity

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

OBSERVATIONAL

Enrollment

100

Start Date

2026-05-05

Completion Date

2036-01

Last Updated

2026-05-14

Healthy Volunteers

No

Interventions

PROCEDURE

Pharmacological or surgical treament of obesity

Longitudinal follow-up of participants who initiate an anti-obesity medication or whose application for bariatric surgery was accepted. It will combine anthropometric, clinical, neuropsychological and biological measurements taken at various timepoints. Participants will be asked to complete a set of online questionnaires and data will be recorded anonymously. Biological samples will be collected at various time points.

Locations (1)

Cliniques Universitaires Saint-Luc

Brussels, Brussels Capital, Belgium