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Systemic Sclerosis DIet for GastrointESTinal Symptoms
Sponsor: University of Michigan
Summary
This research will evaluate the effect of diets on bloating/distention, assess changes in abdominal pain, and overall gastrointestinal symptom burden in Systemic Sclerosis. The researchers will do this by comparing outcomes of people assigned to 3 different diets. Following the research specifics of the diets will be available upon contact with the details listed below.
Official title: SSc-DIGEST Trial: Systemic Sclerosis DIet for GastrointESTinal Symptoms Randomized Controlled Trial of Low FODMAP, CDED, and NICE Diets for Gastrointestinal Symptoms in Systemic Sclerosis
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2026-03-16
Completion Date
2027-04
Last Updated
2026-03-24
Healthy Volunteers
No
Conditions
Interventions
Diet 1: Restriction of fermentable carbohydrates
6 weeks guided diet under the supervision of a dietician restricting fermentable carbohydrates known to trigger GI symptoms.
Diet 2: Elimination of foods harmful to gut barrier and microbiome
6 weeks guided diet under the supervision of a dietician eliminating of foods harmful to gut barrier and microbiome
Diet 3: Regular meal patterns, soluble fiber, and portion control
6 weeks guided diet under the supervision of a dietician emphasizing regular meal patterns, soluble fiber, and portion control.
Locations (1)
University of Michigan
Ann Arbor, Michigan, United States