Clinical Research Directory

Inclusion Criteria: * Patients of both sexes 25-55 y. * Patients who are systemically healthy, * Patient exhibiting periodontal pocket depths (PD) ≥5mm, * Presence of clinical attachment loss (CAL) between 3-4mm, * Cooperative individuals capable of adhering to mechanical oral hygiene instructions Exclusion Criteria: * nPatients with sensitivity to the medication used in the study, * Patients with a history of antibiotic use or anti-inflammatory drugs during the previous 3 months prior to the study, * Patients with systemic diseases, * Pregnant and lactating females, * Smokers and tobacco chewers, * Patients are not compliant with oral hygiene procedures.