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Non-invasive Vagus Nerve Stimulation to Reduce Inflammation and Brain Injury Blood Biomarkers Following an Acute Ischemic Stroke
Sponsor: Washington University School of Medicine
Summary
This is a randomized open-label, with blinded outcome pilot study to evaluate the effect on inflammatory and brain injury laboratory values and explore clinical outcomes in patients who present with ischemic strokes due to large vessel occlusions and are treated with either current accepted management, or accepted management in addition to transcutaneous auricular vagal nerve stimulation.
Official title: Neuromodulation Using Vagus Nerve Stimulation Following Ischemic Stroke as Therapeutic Adjunct 2
Key Details
Gender
All
Age Range
18 Years - 99 Years
Study Type
INTERVENTIONAL
Enrollment
65
Start Date
2026-02-23
Completion Date
2028-02-29
Last Updated
2026-03-02
Healthy Volunteers
No
Interventions
transcutaneous auricular vagal nerve stimulation
Stimulus of the auricular branch of the vagal nerve with the transcutaneous auricular vagal nerve stimulation.
Sham transcutaneous vagal nerve stimulation
Patients assigned to the controls arm will have no electricity applied to the Auricular Branch of the Vagus Nerve.
Locations (1)
Barnes-Jewish Hospital
St Louis, Missouri, United States