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NOT YET RECRUITING
NCT07406334
PHASE1

A Trial to Evaluate the Safety and Reactogenicity of an Investigational Pneumococcal Vaccine in Toddlers 12 to 15 Months of Age Receiving a Single Booster Dose

Sponsor: GlaxoSmithKline

View on ClinicalTrials.gov

Summary

The main purpose of this study is to assess the safety and reactogenicity of a single dose of the new pneumococcal vaccine (called Pn-MAPS30plus) in toddlers who have previously completed a two-dose primary vaccination series with PCV used in local immunization program. PCV20 will be used as a comparator for this study.

Official title: A Phase 1, Observer-Blind, Randomized, Active Controlled Trial to Evaluate the Safety and Reactogenicity of an Investigational Pneumococcal Vaccine in Toddlers 12 To 15 Months of Age Receiving a Single Booster Dose

Key Details

Gender

All

Age Range

12 Months - 15 Months

Study Type

INTERVENTIONAL

Enrollment

45

Start Date

2026-05-15

Completion Date

2027-02-22

Last Updated

2026-02-12

Healthy Volunteers

Yes

Interventions

BIOLOGICAL

Pn-MAPS30plus

Pn-MAPS30plus vaccine will be administered intramuscularly.

COMBINATION_PRODUCT

PCV20

PCV20 vaccine will be administered intramuscularly.