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NOT YET RECRUITING
NCT07408154
PHASE4

Direct vs Standard SLT for Glaucoma: A Noninferiority Trial

Sponsor: Medical University of South Carolina

View on ClinicalTrials.gov

Summary

This study compares two FDA-approved laser treatments for glaucoma: Direct Selective Laser Trabeculoplasty (DSLT) and Selective Laser Trabeculoplasty (SLT). Both procedures aim to lower eye pressure and prevent vision loss. DSLT is a newer, non-contact technique that may improve comfort and efficiency. Participants will be randomly assigned to receive either DSLT or SLT and followed for 12 months to assess eye pressure, safety, and treatment outcomes.

Official title: A Randomized Controlled Trial Comparing Direct Selective Laser Trabeculoplasty (DSLT) and Selective Laser Trabeculoplasty (SLT) in Reducing Intraocular Pressure in Open-Angle Glaucoma

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

172

Start Date

2026-04

Completion Date

2027-05

Last Updated

2026-02-13

Healthy Volunteers

No

Interventions

DEVICE

Direct Selective laser Trabeculoplasty

The Direct Selective Laser Trabeculoplasty is a non-contact laser designed to manage IOP in patients with glaucoma. The traditional SLT required a gonioscopy lens to be placed over the patient's eyes to direct the laser towards the trabecular meshwork.

Locations (1)

MUSC

Charleston, South Carolina, United States