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RECRUITING
NCT07408479
NA

Impact of Starch Digestibility on Glycemic Variability and Control, Cardiometabolic and Inflammatory Profiles, Microbiota and Intestinal Health in Subjects With Insulin Resistance

Sponsor: Mondelēz International, Inc.

View on ClinicalTrials.gov

Summary

To study the potential impact of a diet rich in both Slowly Digestible Starch (SDS) and Resistant Starch (RS), we propose a 2-month nutritional intervention study in which we will study the evolution of carbohydrate variability and metabolism and health-related parameters in 40 volunteers with insulin resistance. Regular sampling of blood, urine and faeces as well as continuous measurement of blood glucose levels will be performed to assess changes in blood glucose levels, insulin resistance, lipid metabolism, inflammation and the composition of the microbiota following the introduction of starch products rich in SDS and RS into the diet.

Key Details

Gender

All

Age Range

18 Years - 75 Years

Study Type

INTERVENTIONAL

Enrollment

40

Start Date

2025-11-15

Completion Date

2028-07

Last Updated

2026-02-13

Healthy Volunteers

Yes

Interventions

OTHER

Balanced diet high in Slowly Digestible Starch and Resistant Starch

Diet where all the starchy foods were selected based on their SDS and RS content. This diet needs to be easy to apply by subjects. It will be consumed during 2 months

OTHER

Balanced diet low in Slowly Digestible Starch and Resistant Starch

Diet where all the starchy foods were selected based on their SDS and RS content. This diet needs to be easy to apply by subjects. It will be consumed during 2 months

Locations (1)

Centre de Recherche en Nutrition Humaine Rhone-Alpes

Lyon, France