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Neurophysiology of Reward Signaling in Parkinson's Disease
Sponsor: Vanderbilt University Medical Center
Summary
The goal of this study is to learn more about the brain activity underlying Parkinson's disease risk taking and reward seeking behaviors. The investigators will utilize neural recordings from corticostriatal structures performed during deep brain stimulation surgery to measure neural activity underlying nonmotor symptoms of Parkinson's disease.
Key Details
Gender
All
Age Range
40 Years - Any
Study Type
INTERVENTIONAL
Enrollment
75
Start Date
2024-09-01
Completion Date
2029-09-30
Last Updated
2026-02-13
Healthy Volunteers
No
Conditions
Interventions
Neurophysiology recordings
Neurophysiology recordings will be performed during deep brain stimulation surgery and their relationship to performance on a gambling task evaluated
Neural stimulation
Neural stimulation will be delivered during a gambling task and its impact on task performance quantified
Locations (1)
Vanderbilt University Medical Center
Nashville, Tennessee, United States