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A Social Network Approach to Improve HIV Prevention and Substance Use Treatment For People Who Use Drugs
Sponsor: NYU Langone Health
Summary
This study includes finalization of the LINKED social network intervention to improve PrEP and MOUD uptake among people who inject drugs (PWID) in collaboration with an Expert Advisory Board and staff (N=16) at The Sidewalk Project (TSP), followed by a Hybrid Type II cluster randomized trial of the LINKED intervention (versus an equal-attention control) among N=372 people who inject drugs, with 6- and 12-month follow-up assessment of PrEP and MOUD uptake. The investigators will also evaluate implementation outcomes to inform future sustainable implementation of LINKED in harm reduction organizations.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
398
Start Date
2027-01
Completion Date
2028-12
Last Updated
2026-02-13
Healthy Volunteers
No
Conditions
Interventions
LINKED
LINKED is a theory-driven social network intervention (SNI) that leverages peer influence within the social networks of people who inject drugs (PWID) to disseminate information, encourage communication, and increase pre-exposure prophylaxis (PrEP) and medications for opioid use disorder (MOUD) uptake and persistence in harm reduction organization (HRO) settings.
Group Intervention
Group intervention facilitated by trained study staff that supports critical thinking about what constitutes low, medium, and high risks for HIV and overdose.
Locations (3)
University of Southern California
Los Angeles, California, United States
The University of Chicago
Chicago, Illinois, United States
NYU Langone Health
New York, New York, United States