Clinical Research Directory

Inclusion Criteria: 1. Age between 16 and 75 years. 2. Diagnosis of Crohn's disease with primary or secondary small bowel stricture confirmed by imaging studies, or small bowel stricture identified by enteroscopy. 3. Inadequate response to conventional medical therapy and step-up treatment strategies. 4. Stricture length less than 5 cm. 5. Signed informed consent form. Exclusion Criteria: 1. Bowel wall thickening with Limberg grade IV blood flow on intestinal ultrasound, or presence of complications such as perforation, fistula, deep ulcer, inflammatory mass, or abscess. 2. Deep ulcer in the stricture segment observed by enteroscopy, potentially involving the muscular layer. 3. Presence of strictures in the esophagus, stomach, or duodenum. 4. Presence of colorectal stricture or ileocecal valve stricture. 5. Small bowel stricture complicated by abscess, fistula, or severe angulation. 6. Patients with ≥3 small bowel strictures or stricture length ≥5 cm. 7. Strictures previously treated with stent placement, dilation, or incision but without sustained symptom-free remission for at least 1 year. 8. Pregnancy or breastfeeding. 9. Inability to undergo endoscopic treatment. 10. Severe coagulation disorders (platelet count \<70,000/μL, INR \>1.5). 11. Concomitant advanced tumors or other severe organ diseases. 12. Suspected localized intestinal malignancy.