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RECRUITING
NCT07409571
NA

Palatal Wound Healing After Free Gingival Graft Surgery

Sponsor: Kahramanmaras Sutcu Imam University

View on ClinicalTrials.gov

Summary

This randomized controlled clinical trial aims to evaluate the effects of topical triamcinolone acetonide application on wound healing and patient-reported outcomes at the palatal donor site following free gingival graft (FGG) surgery. A total of 36 patients with mucogingival deficiencies requiring FGG will be randomly assigned to either a control group receiving a collagen hemostatic sponge or a test group receiving topical triamcinolone acetonide at the donor site. All palatal donor areas will be protected with a periodontal dressing. Clinical assessments will be performed on postoperative days 7, 14, and 30. Wound epithelialization will be evaluated using the hydrogen peroxide bubbling test, while wound healing and scar formation will be assessed using the Landry, Turnbull, and Howley index and the modified Manchester Scar Scale, respectively. Patient-centered outcomes, including postoperative pain, discomfort, analgesic consumption, and oral health-related quality of life, will be assessed using visual analog scales and the Oral Health Impact Profile-14 questionnaire. The findings of this study are expected to provide evidence regarding the potential benefits of topical corticosteroid use in reducing palatal donor site morbidity following FGG surgery.

Official title: The Effect of Topical Triamcinolone Acetonide Application on Wound Healing in the Palatal Donor Site Following Free Gingival Graft Surgery

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

34

Start Date

2026-01-02

Completion Date

2026-03-31

Last Updated

2026-02-13

Healthy Volunteers

Yes

Interventions

DEVICE

Collagen Hemostatic Sponge

A collagen hemostatic absorbable sponge will be applied to the palatal donor site following free gingival graft harvesting to control bleeding and support wound healing. The donor area will be covered with sterile aluminum foil and a periodontal dressing.

DRUG

triamcinolone acetonide

Topical triamcinolone acetonide will be applied to the palatal donor site following free gingival graft harvesting to reduce postoperative inflammation and improve wound healing. The donor area will be covered with sterile aluminum foil and a periodontal dressing.

Locations (1)

Kahramanmaraş Sütçü İmam University

Kahramanmaraş, Kahramanmaraş, Turkey (Türkiye)