Clinical Research Directory

Inclusion Criteria: * Age \> 65 years * MoCA scores 18-25 points * BMI of 20.0 - 29.9 kg/m2 at screening * Stable body weight (≤ 5% change) over the past 3-months * Willing to avoid consuming gut microbiome-modulating dietary supplements within 4 weeks prior to the baseline visit * Subjects will abstain from vitamin B2-rich food intake as per pre-defined list * Maintain current level of physical activity * Be willing and able to comply with trial protocol Exclusion Criteria: * Severe chronic disease and acute injuries * History of dietary supplement use four weeks before enrolment * Organic gastrointestinal (GI) disorders * Bowel surgery or short bowel syndrome * Gut-altering medications two months before enrolment * Is currently using systemic steroids, proton pump inhibitors, H2 blocker, antacid * History of drug and/or alcohol abuse at the time of enrolment * Smoker or vaper * Has made any major dietary changes in the past 3 months prior to baseline * Has a currently active eating disorder * Has food allergies or other issues with foods