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Supersaturated Hydrogen-Rich Water for Outpatients With Persistent Excess Weight
Sponsor: Center for Health Sciences, Serbia
Summary
The Supersaturated Hydrogen-Rich Water for Outpatients with Persistent Excess Weight (HOPE) study is a Phase III, multicenter, randomized, double-blind, placebo-controlled study designed to evaluate the efficacy and safety of daily consumption of supersaturated hydrogen-rich water in adults with persistent excess body weight. The trial investigates whether sustained exposure to molecular hydrogen can favorably influence body composition and key metabolic outcomes compared with a placebo water lacking dissolved hydrogen. By enrolling outpatients across multiple centers and applying rigorous blinding and randomization procedures, HOPE aims to generate high-quality clinical evidence on the potential role of hydrogen-rich water as a non-pharmacological, adjunctive strategy for weight management and metabolic health.
Official title: Supersaturated Hydrogen-Rich Water for Outpatients With Persistent Excess Weight (HOPE)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2026-04-15
Completion Date
2027-02-15
Last Updated
2026-02-13
Healthy Volunteers
Yes
Conditions
Interventions
Hydrogen-rich water
Hydrogen-rich water (1.0 L per day)
Control
Hydrogen-free water (1.0 L per day)
Locations (1)
Center for Health Sciences
Belgrade, Serbia