Clinical Research Directory
Browse clinical research sites, groups, and studies.
Impact of Thyroid Hormones on Human Glucose and Energy Metabolism
Sponsor: University of Ulm
Summary
The goal of this clinical trial to clarify the impact of changes in thyroid hormone levels on glucose and lipid metabolism. Patients will be included in whom thyroid hormone levels are intentionally changed by treatment. In patients with Graves' disease, thyroid hormone levels will be lowered using medication, while in patients with thyroid cancer, thyroid hormone levels will be raised using medication. Oral glucose tolerance tests will be performed before treatment and at two time points after treatment begins to assess metabolic effects.
Key Details
Gender
All
Age Range
Any - Any
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2026-02-04
Completion Date
2031-06
Last Updated
2026-02-13
Healthy Volunteers
No
Conditions
Interventions
Oral Glucose Tolerance Test
Participants will receive a 75 g oral glucose tolerance (3h) before the start of treatment, two weeks and three months after start of treatment. Body composition will measured by bioimpedance analysis. Before and during the oral glucose tolerance test, indirect calometry will assess metabolic flexibility.
Locations (1)
Ulm University Hospital
Ulm, Baden-Wurttemberg, Germany