Clinical Research Directory
Browse clinical research sites, groups, and studies.
Hypiend - Multicomponent Behavioral Intervention in Pre-puberal Children (Hypiend-PPC)
Sponsor: Sciensano
Summary
This study is part of the European Hypiend project, which aims to explore the effects of co-exposure to endocrine disruptor chemicals (EDCs) on the function and epigenetic programming of the hypothalamic-pituitary-adrenal (HPA) axis in order to define intervention strategies to minimize exposure and consequences on the neuroendocrine system during the perinatal and prepubertal phases. The intervention at the perinatal phase is registered under the Unique Protocol ID: 101137440 - Hypiend - Clinical study to evaluate the effectiveness of a multicomponent behavioural intervention to reduce EDC exposure during the perinatal period in women and their offspring. The intervention presented here concerns the prepubertal phase. The primary objective is to demonstrate that a multi-component behavioral intervention (MBI) implemented in primary schools in two different European countries over two and a half school years is effective in reducing the presence of EDCs in the urine of prepubertal children using the Health Action Process Approach (HAPA) and the Positive Behaviour Support (PBS) models to improve the intervention and parents' knowledge of these contaminants, as well as to advance scientific knowledge.
Official title: Understanding and Preventing the Impact of Endocrine Disruptors on the Hypothalamus-pituitary Axis in Sensitive Populations: Study of the Effects of a School and Parental Policy to Minimize Exposure to Endocrine Disruptors Among 6 and 8 Year-olds in the Wallonia-Brussels Federation and Catalunya
Key Details
Gender
All
Age Range
6 Years - 8 Years
Study Type
INTERVENTIONAL
Enrollment
700
Start Date
2025-09-15
Completion Date
2028-12
Last Updated
2026-02-13
Healthy Volunteers
Yes
Interventions
Multi-Component Behavioral intervention
In this intervention, participants will have access to a mobile app that will provide information on EDCs and recommendations and missions to reduce exposure to EDCs. They will also be invited to attend workshops aiming to help them adopting behaviours to reduce exposure to EDCs in their daily life. Intervention will also be applied at the level of the schools.
Information
In this intervention, participants will receive general information on EDCs and placebo workshops
Locations (1)
Sciensano
Brussels, Belgium