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Identification of Women With Severe Insulin Resistant Syndromes of Genetic Origin Among Patients With "Classic" Polycystic Ovary Syndrome (PCOS)
Sponsor: Assistance Publique - Hôpitaux de Paris
Summary
Diagnostic case-control study (1 case for 2 controls). Inclusion of patients with severe insulin resistance syndrome of genetic origin, then inclusion of controls: patients examined for PCOS in day hospital with matching age (+/- 5 years) and Body mass index (+/- 5kg/m2).
Key Details
Gender
FEMALE
Age Range
18 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
81
Start Date
2026-02
Completion Date
2027-09
Last Updated
2026-02-17
Healthy Volunteers
No
Conditions
Interventions
Genetic analysis
Analyses of the insulin resistance and lipodystrophy gene panel revealed pathogenic or highly susceptible variants in control PCOS patients
Biological analysis
Measurement of adipokines
imaging test
DEXA (Dual-Energy X-ray Absorptiometry)
Standard intervention
Standard intervention
Locations (1)
Service Endocrinologie, Hôpital St Antoine
Paris, France