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Non-Surgical Periodontal Therapy and Cardiac Biomarkers in Stable Angina
Sponsor: Ondokuz Mayıs University
Summary
The goal of this clinical study is to learn whether gum treatment can improve heart health. Researchers will compare blood markers related to heart disease before and after routine gum treatment. The main questions this study aims to answer are: Is gum disease a risk factor for heart disease? Can treating gum disease lower the risk of heart disease? Adults with stable angina (a type of heart disease) and adults without heart disease may take part in this study. All participants will receive routine, non-surgical gum treatment, which is a standard dental care procedure. This includes professional cleaning to remove plaque and tartar from the teeth and practical education on tooth brushing and cleaning between the teeth. The treatment will be performed by a single researcher and completed in one visit within about one hour. Participants will: Provide a blood sample before gum treatment Receive routine, non-surgical gum treatment Return after three months for a follow-up visit Provide a second blood sample This study does not involve experimental drugs or devices. Participation is voluntary, and there is no cost to participants. The results may help researchers better understand how gum health is related to heart health.
Official title: Effect of Non-Surgical Periodontal Therapy on Ischemia-Modified Albumin and Soluble ST2 in Patients With Stable Angina
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2026-02-20
Completion Date
2026-08-05
Last Updated
2026-02-17
Healthy Volunteers
Yes
Conditions
Interventions
Non-surgical periodontal therapy (scaling and root planing)
Non-surgical periodontal therapy will include full-mouth scaling and root planing performed using hand instruments and/or ultrasonic devices to remove supra- and subgingival plaque and calculus.
Non-surgical periodontal therapy (Professional dental cleaning)
Supragingival calculus and plaque removal with standardized oral hygiene instruction.
Locations (1)
Ondokuz Mayis University
Samsun, Atakum, Turkey (Türkiye)