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NOT YET RECRUITING
NCT07412795
NA

Non-Surgical Periodontal Therapy and Cardiac Biomarkers in Stable Angina

Sponsor: Ondokuz Mayıs University

View on ClinicalTrials.gov

Summary

The goal of this clinical study is to learn whether gum treatment can improve heart health. Researchers will compare blood markers related to heart disease before and after routine gum treatment. The main questions this study aims to answer are: Is gum disease a risk factor for heart disease? Can treating gum disease lower the risk of heart disease? Adults with stable angina (a type of heart disease) and adults without heart disease may take part in this study. All participants will receive routine, non-surgical gum treatment, which is a standard dental care procedure. This includes professional cleaning to remove plaque and tartar from the teeth and practical education on tooth brushing and cleaning between the teeth. The treatment will be performed by a single researcher and completed in one visit within about one hour. Participants will: Provide a blood sample before gum treatment Receive routine, non-surgical gum treatment Return after three months for a follow-up visit Provide a second blood sample This study does not involve experimental drugs or devices. Participation is voluntary, and there is no cost to participants. The results may help researchers better understand how gum health is related to heart health.

Official title: Effect of Non-Surgical Periodontal Therapy on Ischemia-Modified Albumin and Soluble ST2 in Patients With Stable Angina

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2026-02-20

Completion Date

2026-08-05

Last Updated

2026-02-17

Healthy Volunteers

Yes

Interventions

PROCEDURE

Non-surgical periodontal therapy (scaling and root planing)

Non-surgical periodontal therapy will include full-mouth scaling and root planing performed using hand instruments and/or ultrasonic devices to remove supra- and subgingival plaque and calculus.

PROCEDURE

Non-surgical periodontal therapy (Professional dental cleaning)

Supragingival calculus and plaque removal with standardized oral hygiene instruction.

Locations (1)

Ondokuz Mayis University

Samsun, Atakum, Turkey (Türkiye)