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Comparative Efficacy Of 4 mg VS. 8 mg Submucosal Dexamethasone In Postoperative Pain Management After Dental Implant Surgery: A Randomized Double-Blind Controlled Clinical Trial
Sponsor: Oman Ministry of Health
Summary
This study aims to compare the effectiveness of 4mg and 8mg dexamethasone administered submucosally in reducing postoperative pain after dental implant surgery. Participants will be randomly assigned to receive either 4mg dexamethasone, 8mg dexamethasone, or a placebo (normal saline) at the surgical site. Later, postoperative pain will be assessed using a Visual Analog Scale at 6 hours after the surgery and daily for the next 6 days. Also the number of pain-relief tablets consumed after the surgery will be recorded. Preoperative anxiety will be assessed using Generalized Anxiety Disorder-7 (GAD-7) questionnaire to assess its association with postoperative pain scores. The results of this study will help determine the optimal dose of dexamethasone that is effective for postoperative pain control following dental implant surgery.
Official title: Comparative Efficacy of 4 mg vs. 8 mg Submucosal Dexamethasone in Postoperative Pain Management After Dental Implant Surgery: A Randomized Double-Blind Controlled Clinical Trial
Key Details
Gender
All
Age Range
21 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
138
Start Date
2026-03-25
Completion Date
2026-12-01
Last Updated
2026-03-30
Healthy Volunteers
No
Conditions
Interventions
Dexamethasone 4 Mg/mL Injectable Solution
Syringe will be concealed. Submucosal injection will be adjacent to the surgical site in the buccal vestibule
Dexamethasone 8Mg Solution for Injection
Syringe will be concealed. Submucosal injection will be adjacent to the surgical site in the buccal vestibule
Saline (NaCl 0,9 %) (placebo)
Syringe will be concealed. Submucosal injection will be adjacent to the surgical site in the buccal vestibule
Locations (1)
Al Nahdha Hospital
Muscat, Oman