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Motor Eloquent Navigated Transcranial Magnetic Stimulation for Radiosurgery Planning
Sponsor: Insel Gruppe AG, University Hospital Bern
Summary
With this project, the study group wants to investigate whether a postoperative navigated transcranial magnetic stimulation (nTMS) motor map can improve stereotactic radiosurgery (SRS) planning in patients who underwent resection for a brain metastasis near the primary motor cortex. Specifically, the map could allow for more precise location of motor eloquent tissue, thereby minimizing the radiation dose on these areas while preserving high radiation dose on target tissue (i.e. tumor cells).
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2026-04-01
Completion Date
2029-10-31
Last Updated
2026-02-17
Healthy Volunteers
No
Conditions
Interventions
Navigated Transcranial Magnetic Stimulation (nTMS)
Every patient will undergo a postoperative nTMS motor mapping, and both the "standard" and "nTMS-adapted" SRS plan will be created for every patient. The plan will be selected by the radiation oncologist, depending on whether at least 95% of the dose is administered to the target volume with the "nTMS-adapted" plan or not. Every patient then receives SRS.
Locations (1)
University Hostpital Bern, Department of Neurosurgery Bern
Bern, Switzerland