Clinical Research Directory

Inclusion Criteria: * Adult patients (≥18 years) who are able to communicate clearly. * Diagnosis of renal disease or confirmed requirement for protein supplementation by a suitably qualified health care professional (e.g. dietitian) * Participants with or at risk of malnutrition as determined by the SGA nutritional screening tool, MUST and/or by professional clinical judgement. * Participants expected to require an ONS for at least 28 days from baseline, to take flavour variants orally and neutral via feeding tube. * Informed consent obtained. Exclusion Criteria: * Participation in any other studies involving investigational or marketed products concomitantly or within seven days prior to entry into the study * Patients with medical or dietary contraindication to any ingredients (see appendix 2 of protocol for full list.) * No feeding tube for any patient taking the neutral variant. * Patients with significant hepatic impairment. * Patients with dysphagia requiring IDDSI level 1 (or higher) fluids. * Patients with uncontrolled inflammatory bowel disease or previous bowel resection with ongoing gastrointestinal symptoms. * Any patients having taken antibiotics over the previous 2 weeks leading up to the study. * Any participant unable to give consent i.e., those with dementia. * Participants under 18 years of age. * Individuals who do not have sufficient proficiency with English language * Investigator's uncertainty about the willingness or ability of the patient to comply with the protocol requirements.