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Comparison of Two Different Doses of Phenylephrine on Oxytocin Hemodynamic Effect
Sponsor: Rawalpindi Medical College
Summary
Cesarean section is one of the commonly performed surgical procedures in the world. Once baby is delivered during the surgical procedure anesthesiologist administer Oxytocin drug through IV cannula which helps the Uterus to contract so that excessive blood loss doesnt occur. But this is associated with fall in blood pressure frequently requiring administration of medications to treat low blood pressure. The most frequently used drug is phenylephrine which can administered along with oxytocin to prevent fall in blood pressure. This study will compare to different doses of Phenylephrine to prevent fall in blood pressure.
Official title: Effects of Two Different Doses of Phenylephrine co Administration on Oxytocin- Induced Hemodynamic Effects
Key Details
Gender
FEMALE
Age Range
20 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
112
Start Date
2026-02-13
Completion Date
2026-07-13
Last Updated
2026-02-24
Healthy Volunteers
Yes
Conditions
Interventions
Phenylephrine bolus 75 micrograms
After delivery of Baby during C section, patient will be administered 3 IU of Oxytocin over 3 minutes along with 75 micrograms of Phenylephrine Intravenously.
Phenylephrine bolus 50 micrograms
After delivery of Baby during C section, patient will be administered 3 IU of Oxytocin over 3 minutes along with 50 micrograms of Phenylephrine Intravenously.
Locations (1)
Department of Anesthesia, Holy Family Hospital, Rawalpindi
Rawalpindi, Punjab Province, Pakistan