Mechanical Insufflation-Exsufflation in Critically Ill Patients

NOT YET RECRUITING

NCT07420946

Sponsor: Medipol University

Summary

Mechanical insufflation-exsufflation (MI-E) is an established airway clearance technique for patients with chronic conditions like neuromuscular diseases. However, its use in critically ill ICU patients remains inconsistent and lacks standardized guidelines. Despite growing research, current practices vary widely in patient selection, treatment protocols, and safety management, with limited high-quality evidence to support clear recommendations. To address this gap, an international, multidisciplinary Delphi consensus study is needed to establish expert-based best practices and feasible guidelines for the safe and effective implementation of MI-E in the intensive care setting.

Official title: Mechanical Insufflation-Exsufflation in Critically Ill Patients: An International DELphi Consensus (DELMI-E)

Key Details

Gender

All

Age Range

Any - Any

Study Type

OBSERVATIONAL

Enrollment

30

Start Date

2026-03-01

Completion Date

2026-12-01

Last Updated

2026-02-19

Healthy Volunteers

No

Conditions

Airway Clearance Mechanical Insufflation-exsufflation Mechanical Insufflation-exsufflation Session ( With Cough Assist)Delphi Study Consensus Critical Illness Critical Care Critical Care, Intensive Care

Interventions

OTHER

Delphi Questionnaire

Statements on MI-E topics, rated along their level of appropriateness on a scale from 1 to 5. Multiple rounds are organised to reach consensus on a topic.

Locations (4)

Monaldi Hospital A.O.R.N. dei Colli

Naples, Italy

University of Naples Federico II

Naples, Italy

Hospital General Universitario Morales Meseguer

Murcia, Spain

İstanbul Medipol University

Istanbul, Istanbul, Turkey (Türkiye)

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