Clinical Research Directory
Browse clinical research sites, groups, and studies.
Intravenous Nalbuphine Versus Lidocaine for Prevention of Propofol Injection Pain
Sponsor: Hayatabad Medical Complex
Summary
Propofol is a commonly used intravenous anesthetic agent, but its administration is frequently associated with injection pain, causing patient discomfort and agitation. Various pharmacological agents have been used to reduce this pain, including nalbuphine and lidocaine; however, results from previous studies remain conflicting. This randomized clinical trial aims to compare the effectiveness of intravenous nalbuphine versus intravenous lidocaine in reducing the frequency of propofol-induced injection pain in patients undergoing elective general surgery procedures.
Official title: Comprasion of Intravenous Nalbuphine Versus Lidocaine in Reducing Propofol -Induced Injection Pain During General Surgery Procedure
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
92
Start Date
2026-03-01
Completion Date
2026-08-01
Last Updated
2026-02-20
Healthy Volunteers
Yes
Conditions
Interventions
Nalbuphine
Intravenous nalbuphine 0.1mg/kg administred 60second prior to induction with propofol
Lidocaine
Intravenous lidocaine 4.5mg/kg (maximum 300mg) administred 60sec prior to induction with propofol