Clinical Research Directory

Inclusion Criteria: Clinical inclusion criteria: * NSTEMI, STEMI * Symptom duration \<12h for STEMI and \<48h for NSTEMI * Age ≥ 18yrs * Ability to provide written informed consent Angiographic inclusion criteria: * Angiographic signs of at least one possible culprit lesion. Signs including acute occlusion, partial occlusion, proximal embolus, haziness, high grade stenosis, stent thrombosis * Wire in true distal lumen Exclusion Criteria: Clinical exclusion criteria * Intravascular imaging evaluation of any lesions at index procedure * Cardiogenic shock * Sustained ventricular tachycardia or ventricular fibrillation * Planned CABG * Life expectancy \<1 year * Known severe heart failure with NYHA class equal or above III * Known ejection fraction \<30% before the admission * Known renal failure with GFR \<30 ml/min/1.73 m2 * Active bleeding or coagulopathy * Relevant allergies (contrast media, aspirin, clopidogrel, ticagrelor, everolimus) * Suspected inability to lie flat for the duration of the PCI procedure * Inability to comply with the planned follow-up program * Known or anticipated compliance problems with medical therapy Angiographic exclusion criteria * Study lesion involving the Left main coronary artery * Study lesion involving a true bifurcation lesion with a SB \>2.5mm * Severe tortuosity * Distal embolus * Isolated coronary artery spasm * Suspected spontaneous coronary artery dissection * Chronic total occlusions with treatment indication and no antegrade intra plaque wire pass