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The Impact of Continuous Glucose Monitoring on Glucose Variability and Weight Loss in Individuals With Prediabetes and Obesity
Sponsor: University of Primorska
Summary
This randomized, crossover interventional study evaluates the effects of real-time (open) versus blinded continuous glucose monitoring (CGM) on glycemic variability, lifestyle behaviors, and metabolic outcomes in adults with prediabetes and overweight or obesity (BMI ≥ 27 kg/m²). Thirty participants will undergo both open and blinded CGM phases, separated by a washout period. The study aims to assess whether access to real-time glucose data promotes behavioral change and improves metabolic health compared with blinded CGM use.
Official title: The Impact of Continuous Glucose Monitoring on Behavioral Change, Glucose Variability and Weight Loss in Individuals With Prediabetes and Obesity - a Randomized Crossover Study
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
34
Start Date
2026-05-01
Completion Date
2027-06-01
Last Updated
2026-04-03
Healthy Volunteers
No
Conditions
Interventions
Continuous Glucose Monitoring (CGM)
Use of a continuous glucose monitoring system to measure interstitial glucose levels. During the open CGM phase, participants have real-time access to glucose data; during the blinded CGM phase, glucose data are masked from participants.
Locations (3)
University of Primorska, Faculty of Health Sciences
Izola, Slovenia
Diabetes Outpatient Clinic, Community Health Center Koper, Slovenia
Koper, Slovenia
Department Of endocrinology and diabetes, Medical Faculty, University of Ljubljana
Ljubljana, Slovenia