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Early Detection of Brain Injury After Congenital Heart Surgery in Infants
Sponsor: University Medical Centre Ljubljana
Summary
Infants with congenital heart disease undergoing cardiac surgery with extracorporeal circulation are at risk for perioperative hypoxic-ischaemic brain injury. This prospective, single-centre observational cohort study will evaluate perioperative dynamics of serum biomarkers of neuronal, glial, and axonal injury and relate biomarker patterns to postoperative EEG changes and brain MRI findings, aiming to improve early detection of brain injury and identify children at higher risk of hypoxic encephalopathy.
Official title: Early Detection of Brain Damage in Children With Congenital Heart Disease After Cardiovascular Surgery
Key Details
Gender
All
Age Range
10 Days - 1 Year
Study Type
OBSERVATIONAL
Enrollment
30
Start Date
2024-05-03
Completion Date
2026-09
Last Updated
2026-03-10
Healthy Volunteers
No
Interventions
Observational study: blood analisys, EEG, MRI
Observational study: blood analisys, EEG, MRI
Locations (1)
University Medical Center
Ljubljana, Slovenia