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Multicenter Study of Transcranial Magnetic Stimulation on Vision Restoration
Sponsor: Shanghai High Myopia Study Group
Summary
The goal of this clinical trial is to learn if transcranial magnetic stimulation (TMS) works to restore vision in adults with severe retinal degeneration. It will also learn about the safety of TMS treatment. The main questions it aims to answer are: 1. Does TMS treatment improve the visual function of participants? 2. What medical problems do participants have when receiving TMS treatment? Researchers will compare TMS treatment to a sham stimulation (identical procedures using a sham coil without effective magnetic field output) to see if TMS treatment works to restore their vision. Participants will: UndergoTMS treatment to a sham stimulation for consecutive 5 days Visit the clinic at 5 days, 4 weeks, 3 months, 6 months, 12 months after start of the treatment for checkups and tests
Official title: Effectiveness of TMS for Visual Restoration: a Multicenter Randomized Controlled Trial
Key Details
Gender
All
Age Range
45 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
136
Start Date
2026-06-01
Completion Date
2029-05-31
Last Updated
2026-02-23
Healthy Volunteers
No
Interventions
Transcranial magnetic stimulation targeting occipital visual cortex
Transcranial magnetic stimulation targeting occipital visual cortex
Sham stimulation
identical procedure using a sham coil without effective magnetic field output
Locations (4)
Hong Kong Polytechnic University
Hong Kong, China
Eye and Ear, Nose, Throat Hospital of Fudan University
Shanghai, China
Huadong Hospital of Fudan University
Shanghai, China
Shanghai Ninth People's Hospital
Shanghai, China