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Role of Elevated Lactate Levels on Lipid and Carbohydrate Metabolism.
Sponsor: Ricardo Mora
Summary
The purpose of this study is to investigate whether the elevated circulating lactate levels of individuals with metabolic syndrome are responsible for their reduced lipolysis and glucose tolerance. The investigators will conduct an intervention study in which blood lactate levels will be elevated via intravenous infusion of sodium lactate. State of the art metabolic assessment using stable isotopes and indirect calorimetry will be used to study alterations in fat and carbohydrate metabolism.
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
24
Start Date
2026-01-20
Completion Date
2028-09-30
Last Updated
2026-02-23
Healthy Volunteers
Yes
Interventions
hyperlactacidemia
Raise blood lactate in metabolically healthy individuals to the levels of individuals with metabolic syndrome
Saline (0.9%, sterile, for infusion)
Saline infusion as a control treatment
Locations (1)
Facultad de Ciencias del Deporte
San Javier, Murcia, Spain