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Close Chain and Open Chain Exercises With Blood Flow Restriction in Knee Osteoarthritis
Sponsor: Riphah International University
Summary
The aim of this research is to find and compare the effect of close chain and open chain exercises with blood flow restriction in knee osteoarthritis on pain, range of motion, strength and functional performance in patients with knee osteoarthritis. Randomized controlled trials done at Railway General Hospital and Medistic Medical and Dental Center, Rawalpindi. The sample size was 40. The subjects were divided in two groups, 20 subjects in close chain exercises with blood flow restriction group and 20 in open chain exercises with blood flow restriction group. Study duration was of 4 weeks. Sampling technique applied was purposive non probability sampling technique. Only 45-75 years individual with grade 1 or 2 knee osteoarthritis were included. Tools used in the study are Numeric pain rating scale (NPRS), Western Ontario and McMaster Universities Arthritis Index (WOMAC), goniometer, crane scale (dynamometer), 30 s chair stand test. Data was analyzed through SPSS 21.
Official title: Comparison of Close Chain and Open Chain Exercises With Blood Flow Restriction in Knee Osteoarthritis
Key Details
Gender
All
Age Range
45 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2026-02-28
Completion Date
2026-06-30
Last Updated
2026-02-23
Healthy Volunteers
No
Conditions
Interventions
Closed kinetic chain exercises with blood flow restriction
Closed kinetic chain exercises with blood flow restriction and conservative therapy. Participants in this group will receive conventional physiotherapy including hot pack application over the knee for 10 minutes and TENS applied medial and lateral to the knee for 10 minutes prior to exercises. Mulligan mobilization with movement will be performed using pain free sustained tibial glides during active knee flexion and extension. Closed kinetic chain quadriceps strengthening exercises will include seated heel press, mini squats, wall slides, step ups, and step downs performed under blood flow restriction. Exercises will be performed using a standardized blood flow restriction protocol of 4 sets with repetitions of 30, 15, 15, and 15 at low load. Sessions will be conducted 3 days per week for 4 weeks, with a total of 12 sessions, each session lasting approximately 40 minutes.
Open kinetic chain exercises with blood flow restriction
Open kinetic chain exercises with blood flow restriction and conservative therapy. Participants in this group will receive conventional physiotherapy including hot pack application over the knee for 10 minutes and TENS applied medial and lateral to the knee for 10 minutes prior to exercises. Mulligan mobilization with movement will be performed using pain free sustained tibial glides during active knee flexion and extension. Open kinetic chain quadriceps strengthening exercises will include straight leg raises and knee extension exercises performed under blood flow restriction. Exercises will be performed using a standardized blood flow restriction protocol of 4 sets with repetitions of 30, 15, 15, and 15 at low load. Sessions will be conducted 3 days per week for 4 weeks, with a total of 12 sessions, each session lasting approximately 40 minutes
Locations (2)
Medistic Medical and Dental Center
Rawalpindi, Pakistan
Pakistan Railway General Hospital
Rawalpindi, Pakistan