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Amygdala Insula Retraining in the Management of Perimenopause Symptoms
Sponsor: Chronic Conditions Research Fund
Summary
The goal of this study is to evaluate a neuroplasticity-based mind-body intervention, Amygdala and Insula Retraining (AIR), compared to a wait-list control in individuals experiencing perimenopausal symptoms. Our research questions include: Does AIR reduce overall perimenopausal symptom burden compared to a wait-list control? Does AIR improve sleep disturbance, vasomotor symptom interference, fatigue, mood, anxiety, and quality of life in perimenopausal individuals? Are symptom changes associated with improvements in autonomic regulation and sleep parameters, as reflected by exploratory wearable measures including heart rate variability?
Key Details
Gender
FEMALE
Age Range
38 Years - 61 Years
Study Type
INTERVENTIONAL
Enrollment
160
Start Date
2026-03-01
Completion Date
2026-09-01
Last Updated
2026-02-23
Healthy Volunteers
No
Conditions
Interventions
Amygdala and Insula Retraining (AIR)
Mind-body brain retraining intervention
Locations (1)
Luther College Department of Psychology
Decorah, Iowa, United States