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Sex Differences in Exercise-Induced Hypoalgesia
Sponsor: Centro Universitario La Salle
Summary
Exercise-induced hypoalgesia (EIH) refers to the reduction in pain sensitivity following acute exercise. Although aerobic exercise has been shown to induce hypoalgesia in healthy individuals, it remains unclear whether the magnitude of this response differs between men and women. This quasi-experimental study aims to evaluate sex differences in pressure pain thresholds following a standardized aerobic exercise protocol using a lower-limb cycle ergometer. Pressure pain thresholds will be assessed before exercise, immediately after exercise, and 30 minutes after exercise in healthy adults aged 18 to 65 years. The findings of this study may contribute to improving individualized exercise prescription strategies based on sex differences in pain modulation.
Official title: Sex Differences in Exercise-Induced Hypoalgesia Following Aerobic Exercise Using a Lower-Limb Cycle Ergometer: A Quasi-Experimental Study
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2026-03-15
Completion Date
2026-07-15
Last Updated
2026-03-18
Healthy Volunteers
Yes
Conditions
Interventions
Aerobic exercise using cycle ergometer
Participants will perform a 30-minute aerobic exercise protocol using a lower-limb cycle ergometer at 70% heart rate reserve. The protocol includes: * 5-minute warm-up * 20-minute exercise at target intensity * 5-minute cool-down Heart rate will be monitored continuously using a validated heart rate monitor.
Locations (1)
Centro Superior de Estudios Universitarios La Salle
Madrid, Madrid, Spain