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SPARK Study - Sympathetic Periarterial Radial Block in Healthy Volunteers
Sponsor: Duke University
Summary
The SPARK Study evaluates changes in peripheral sympathetic vasomotor activity following a targeted, ultrasound-guided periarterial sympathetic block of the distal radial artery in healthy volunteers. Autonomic reactivity will be assessed before and after the block using digit-specific pulse-amplitude index and infrared thermography during standardized cold pressor testing.
Official title: SPARK Study - Sympathetic PeriArterial Radial blocK Study
Key Details
Gender
All
Age Range
18 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2026-05
Completion Date
2027-04
Last Updated
2026-04-01
Healthy Volunteers
Yes
Conditions
Interventions
Lidocaine 2%
Small-volume injection (5 mL) of 2% lidocaine around radial artery under ultrasound guidance.
Locations (1)
Duke University Medical Center
Durham, North Carolina, United States