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Buprenorphine for Analgesia in Older Adults With Acute Fractures in the Emergency Department: a Randomized Controlled Study
Sponsor: The Cooper Health System
Summary
The goal of this clinical trial is to learn if buprenorphine can treat pain in older adults who have broken bones. The main questions it aims to answer are: Is buprenorphine as effective as opioids to treat pain? Are there less side effects with buprenorphine? Researchers will compare buprenorphine and hydromorphone to see if there are differences in pain control and side effects. Participants will be given one of the two study drugs after breaking a bone and asked about their pain scores and side effects for the next 48 hours.
Key Details
Gender
All
Age Range
65 Years - Any
Study Type
INTERVENTIONAL
Enrollment
48
Start Date
2026-04
Completion Date
2027-01
Last Updated
2026-02-24
Healthy Volunteers
No
Conditions
Interventions
Buprenorphine 0.15 MG
given every 15 minutes as needed for numerical pain score 4 or greater for a maximum of three doses
Hydromorphone 0.25 mg IV
given every 15 minutes as needed for numerical pain score 4 or greater for a maximum of three doses
Locations (1)
Cooper University Hospital
Camden, New Jersey, United States