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Topical Carboxytherapy Paste Following Microneedling
Sponsor: Vanderbilt University Medical Center
Summary
Topical carboxytherapy refers to a gel paste that carries non-gaseous carbon dioxide (CO2). It is applied similarly to a face mask. Topical carboxytherapy has been shown to increase local blood flow and can help with wound healing. Few studies have researched how topical carboxytherapy can be used to aid skin rejuvenation in the field of facial plastic and reconstructive surgery. The goal of this study is to evaluate how topical carboxytherapy can improve skin healing after microneedling. Common temporary side effects of microneedling include redness and swelling, sometimes lasting up to a week post-procedure. If topical carboxytherapy reduces downtime related to side effects of microneedling, the investigators may offer this treatment to more microneedling patients in the future.
Official title: Effect of Topical Carboxytherapy Paste Following Microneedling
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2026-03-01
Completion Date
2026-06-30
Last Updated
2026-02-24
Healthy Volunteers
Yes
Conditions
Interventions
CO2 gel mask
CO2 gel mask will be applied to one half of the face for 40 minutes after microneedling