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NOT YET RECRUITING
NCT07431541
PHASE1/PHASE2

Topical Carboxytherapy Paste Following Microneedling

Sponsor: Vanderbilt University Medical Center

View on ClinicalTrials.gov

Summary

Topical carboxytherapy refers to a gel paste that carries non-gaseous carbon dioxide (CO2). It is applied similarly to a face mask. Topical carboxytherapy has been shown to increase local blood flow and can help with wound healing. Few studies have researched how topical carboxytherapy can be used to aid skin rejuvenation in the field of facial plastic and reconstructive surgery. The goal of this study is to evaluate how topical carboxytherapy can improve skin healing after microneedling. Common temporary side effects of microneedling include redness and swelling, sometimes lasting up to a week post-procedure. If topical carboxytherapy reduces downtime related to side effects of microneedling, the investigators may offer this treatment to more microneedling patients in the future.

Official title: Effect of Topical Carboxytherapy Paste Following Microneedling

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2026-03-01

Completion Date

2026-06-30

Last Updated

2026-02-24

Healthy Volunteers

Yes

Conditions

Interventions

DRUG

CO2 gel mask

CO2 gel mask will be applied to one half of the face for 40 minutes after microneedling