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RECRUITING
NCT07431866
PHASE1

A Clinical Study of the Effect of MK-2828 on Rosuvastatin or Furosemide in Healthy People (MK-2828-005)

Sponsor: Merck Sharp & Dohme LLC

View on ClinicalTrials.gov

Summary

Researchers are looking for other ways to treat people who have heart failure with preserved ejection fraction (HFpEF). HFpEF is a type of heart failure where the heart becomes stiff and does not relax properly. MK-2828 is a study medicine designed to treat HFpEF. The main goal of the study is to learn if MK-2828 affects what happens to rosuvastatin or furosemide in the body.

Official title: A Two-Part Clinical Study to Evaluate the Effect of Multiple Doses of MK-2828 on Rosuvastatin (Part 1) and Furosemide (Part 2) in Healthy Participants

Key Details

Gender

All

Age Range

24 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

39

Start Date

2026-03-18

Completion Date

2026-06-07

Last Updated

2026-03-25

Healthy Volunteers

Yes

Conditions

Interventions

DRUG

Rosuvastatin

Oral administration

DRUG

Furosemide

Oral administration

DRUG

MK-2828

Oral administration

Locations (1)

Fortrea Clinical Research Unit Inc ( Site 0001)

Daytona Beach, Florida, United States