Clinical Research Directory
Browse clinical research sites, groups, and studies.
Single-step vs Stepwise Lung Recruitment Maneuvers After Cardiopulmonary Bypass
Sponsor: Ondokuz Mayıs University
Summary
This prospective randomized controlled trial aims to compare the hemodynamic and pulmonary effects of single-step and stepwise lung recruitment maneuvers in adult patients undergoing elective cardiac surgery with cardiopulmonary bypass. After separation from cardiopulmonary bypass, patients will be randomized to receive either a single-step sustained inflation recruitment maneuver or a stepwise incremental recruitment maneuver, both combined with 8 cmH₂O positive end-expiratory pressure. The primary outcome is the change in cardiac index before and after the recruitment maneuver. Secondary outcomes include lung ultrasound atelectasis score, and hemodynamic parameters.
Official title: Comparison of Hemodynamic and Pulmonary Outcomes Between Single-Step and Stepwise Lung Recruitment Maneuvers After Cardiopulmonary Bypass: A Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
52
Start Date
2026-02-15
Completion Date
2027-05-01
Last Updated
2026-04-06
Healthy Volunteers
No
Conditions
Interventions
Single Step Lung Recruitment Maneuver
A sustained inflation lung recruitment maneuver with an airway pressure of 30 cmH₂O applied for 30 seconds after separation from cardiopulmonary bypass, combined with 8 cmH₂O positive end-expiratory pressure.
Stepwise Lung Recruitment Maneuver
A stepwise lung recruitment maneuver in which airway pressure is increased by 5 cmH₂O every 5 seconds up to 30 cmH₂O and then decreased in the same manner after separation from cardiopulmonary bypass, combined with 8 cmH₂O positive end-expiratory pressure.
Locations (1)
Ondokuz Mayıs University, Faculty of Medicine
Samsun, Atakum, Turkey (Türkiye)