Clinical Research Directory

Inclusion Criteria: * Aged 18-75 years, willing to sign the ICF * Diagnosed with plaque psoriasis for at least 6 months prior to screening. * At screening and baseline, PASI score ≥ 12 points, BSA ≥ 10%, sPGA ≥ 3 * Be eligible for phototherapy or systemic therapy. Exclusion Criteria: * Non-plaque psoriasis (ie, guttate, pustular, erythrodermic, or inverse psoriasis) within 3 months prior to baseline. * Other skin diseases at screening or baseline Drug-induced psoriasis. * History of severe herpes zoster or severe herpes simplex or current herpes simplex/zoster infection. * History of a serious bacterial, fungal, or viral infection requiring hospitalization or intravenous antimicrobial therapy within 3 months prior to the first dose. * History of a bacterial, fungal, or viral infection requiring oral antimicrobial therapy within 4 weeks prior to the first dose. * Active infection or acute illness within 7 days prior to the first dose. Chronic or recurrent infectious diseases at screening or baseline that, in the investigator's judgment, may increase safety risks. * Evidence of active TB. Patients with evidence of latent tuberculosis may enter the trial after sufficient treatment had initiated and maintained according to protocol. * History of a major or unstable clinical condition within 6 months prior to the first dose, which would compromise participation. * History of malignant tumour within 5 years before screening. * Previous or current autoimmune diseases. * Positive results of confirmatory test for hepatitis B, hepatitis C, human immunodeficiency virus (HIV) or syphilis. * Allergic to any component of the investigational drug.