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NOT YET RECRUITING
NCT07433972
NA

Changes in Hemodynamic Response Following Transcranial Electrical Stimulation in Sroke Individuals

Sponsor: Mahidol University

View on ClinicalTrials.gov

Summary

The present study will use transcranial electrical stimulation (tES) which are transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS) combined with conventional physical therapy and cognitive-motor dualt ask gait training in sub-acute (at least 2 weeks after stroke onset) to chronic stroke (within 5 years post-stroke) to investigate changes in brain hemodynamics (oxy-hemoglobin and deoxy-hemoglobin concentration) as measured by functional near infrared spectroscopy (fNIRS). The findings may provides insights changes in combining tES with rehabilitation on improvements in brain hemodynamics in sub-acute to chronic stroke.

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2026-03-01

Completion Date

2026-12-30

Last Updated

2026-02-25

Healthy Volunteers

No

Interventions

DEVICE

Transcranial direct current stimulation

The direct current is set at 2.0 mA, delivered for 20 minutes with ramp-up and ramp-down for 30 seconds. The electrodes are placed over lesional M1

DEVICE

transcranial alternating current stimulation

The alternating current is set at 2.0 mA, 70 Hz delivered for 20 minutes with ramp-up and ramp-down for 30 seconds. The electrodes are placed over lesional M1

OTHER

Rehabilitation program

Conventional physical therapy and cognitive motor-dual task gait training will be provided immediately after stimulation ends. The rehabilitation program will be provided by licensed physiotherapist

DEVICE

transcranial electrical stimulation (Sham)

The direct current is set at 2.0 mA delivered for 1 minutes with ramp-up and ramp-down for 30 seconds. However, participants remains wearing electrodes cap until 20 minutes. The electrodes are placed over lesional M1

Locations (1)

Faculty of Physical Therapy, Mahidol University

Salaya, Changwat Nakhon Pathom, Thailand