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ACTIVE NOT RECRUITING
NCT07434141
NA

Postoperative Pain After Single-Cone Root Canal Obturation Using Three Sealers

Sponsor: Tehran University of Medical Sciences

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to compare post-treatment pain after root canal therapy in adults with irreversible pulpitis using different root canal sealers. The study will also evaluate the need for pain medication after treatment. The main questions this study aims to answer are: Does the type of root canal sealer affect the intensity of pain after treatment? Does the type of sealer influence the number of analgesic tablets taken by participants? How does pain change over time after treatment with different sealers? Researchers will compare two bioceramic sealers (EndoSeal TCS and NeoSeal) with a resin-based sealer (AH Plus) to determine their effects on post-endodontic pain. Participants will: Receive root canal treatment using one of the study sealers Report their pain intensity at specific time points after treatment Record the number of analgesic tablets taken during the follow-up period

Official title: Comparative Analysis of Postoperative Pain in Symptomatic Irreversible Pulpitis Teeth Following Single Cone Obturation Using Three Different Sealers: A Randomized Clinical Trial

Key Details

Gender

All

Age Range

18 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

75

Start Date

2025-06-08

Completion Date

2026-05-30

Last Updated

2026-02-25

Healthy Volunteers

Yes

Interventions

PROCEDURE

Endoseal TCS

Bioceramic, premixed calcium silicate-based root canal sealer used for obturation with the single-cone technique during root canal treatment

PROCEDURE

Neosealer

Fast-setting calcium silicate-based bioceramic root canal sealer used for obturation with the single-cone technique during root canal treatment

PROCEDURE

AH Plus

Epoxy resin-based root canal sealer used for obturation with the single-cone technique during root canal treatment

Locations (1)

Tehran University of Medical Sciences, School of Dentistry

Tehran, Iran