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Postoperative Pain After Single-Cone Root Canal Obturation Using Three Sealers
Sponsor: Tehran University of Medical Sciences
Summary
The goal of this clinical trial is to compare post-treatment pain after root canal therapy in adults with irreversible pulpitis using different root canal sealers. The study will also evaluate the need for pain medication after treatment. The main questions this study aims to answer are: Does the type of root canal sealer affect the intensity of pain after treatment? Does the type of sealer influence the number of analgesic tablets taken by participants? How does pain change over time after treatment with different sealers? Researchers will compare two bioceramic sealers (EndoSeal TCS and NeoSeal) with a resin-based sealer (AH Plus) to determine their effects on post-endodontic pain. Participants will: Receive root canal treatment using one of the study sealers Report their pain intensity at specific time points after treatment Record the number of analgesic tablets taken during the follow-up period
Official title: Comparative Analysis of Postoperative Pain in Symptomatic Irreversible Pulpitis Teeth Following Single Cone Obturation Using Three Different Sealers: A Randomized Clinical Trial
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
75
Start Date
2025-06-08
Completion Date
2026-05-30
Last Updated
2026-02-25
Healthy Volunteers
Yes
Conditions
Interventions
Endoseal TCS
Bioceramic, premixed calcium silicate-based root canal sealer used for obturation with the single-cone technique during root canal treatment
Neosealer
Fast-setting calcium silicate-based bioceramic root canal sealer used for obturation with the single-cone technique during root canal treatment
AH Plus
Epoxy resin-based root canal sealer used for obturation with the single-cone technique during root canal treatment
Locations (1)
Tehran University of Medical Sciences, School of Dentistry
Tehran, Iran